Peptide
Argireline (Acetyl Hexapeptide-3)
Acetyl Hexapeptide-3
Also known as: Acetyl Hexapeptide-3, Acetyl Hexapeptide-8
Argireline (acetyl hexapeptide-3) is a synthetic peptide that inhibits the SNARE complex, reducing the release of neurotransmitters that cause muscle contractions. This provides a mild botox-like effect on expression lines. Clinical evidence supports its efficacy for reducing crow's feet and forehead lines. Most effective in leave-on formulations applied to areas of repeated muscle movement.
Ingredient Profile
INCI Name
Acetyl Hexapeptide-3
Common Name
Argireline (Acetyl Hexapeptide-3)
Category
Peptide
Function
Anti-ageing, expression line reduction
Typical Usage Rate
0.001–0.01%
Comedogenic
0/5 — Non-comedogenic
Comedogenicity ratings are based on the rabbit ear assay model. Individual skin responses vary. See our article on comedogenicity ratings for context.
Suitable Skin Types
MatureNormal
Addresses
Expression linesCrow's feetForehead lines
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