Peptide

Matrixyl (Palmitoyl Pentapeptide-4)

Palmitoyl Pentapeptide-4

Also known as: Palmitoyl Pentapeptide-4, Matrixyl 3000

Matrixyl (palmitoyl pentapeptide-4) is a signal peptide that mimics a fragment of collagen, signalling the skin to produce more collagen and hyaluronic acid. Clinical studies show it reduces wrinkle depth and improves skin firmness. One of the most well-researched cosmetic peptides with a strong evidence base. Works best in stable, low-pH formulations.

Ingredient Profile

INCI Name
Palmitoyl Pentapeptide-4
Common Name
Matrixyl (Palmitoyl Pentapeptide-4)
Category
Peptide
Function
Anti-ageing, collagen stimulation
Typical Usage Rate
0.001–0.01%
Comedogenic
0/5 — Non-comedogenic

Comedogenicity ratings are based on the rabbit ear assay model. Individual skin responses vary. See our article on comedogenicity ratings for context.

Suitable Skin Types

MatureNormal

Addresses

AgeingFine linesCollagen loss

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