Also known as: Palmitoyl Pentapeptide-4, Matrixyl 3000
Matrixyl (palmitoyl pentapeptide-4) is a signal peptide that mimics a fragment of collagen, signalling the skin to produce more collagen and hyaluronic acid. Clinical studies show it reduces wrinkle depth and improves skin firmness. One of the most well-researched cosmetic peptides with a strong evidence base. Works best in stable, low-pH formulations.
Comedogenicity ratings are based on the rabbit ear assay model. Individual skin responses vary. See our article on comedogenicity ratings for context.
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